Ferroptosis as a novel driver of inflammation in lupus nephritis
Erika Boesen, PhD
University of Nebraska Medical Center
Grants
Novel Research Grants (Novel)
Novel Research Grants offer up to $100,000/year total costs for up to 3 years. They provide early stage support for highly innovative approaches to major challenges in lupus research. Special emphasis is placed on lupus studies exploring fundamental mechanisms, novel targets and pathways, novel technologies, and interdisciplinary approaches.
2018 Funded Grants
Erika Boesen, PhD
University of Nebraska Medical Center
Lymphatic Regulation and Photosensitivity
Theresa Lu, MD, PhD
The Hospital for Special Surgery
Age-Associated B cells in Autoimmune Lupus
Kevin Nickerson, PhD
University of Pittsburgh
Genetically Engineering Regulatory T Cells to Treat SLE
Joshua Ooi, PhD
Monash University
Examining the Role of T cell Exhaustion in Lupus Pathogenesis
Jeremy Tilstra, MD, PhD
University of Pittsburgh
Epigenetic Regulation of Il2 by ATF7ip – Implications for SLE
Michael Waterfield, MD, PhD
University of California, San Francisco (Contracts & Grants)
2017 Funded Grants
Immunotargeting of T Follicular Helper (Tfh) Cells for SLE Treatment
Andre Ballesteros-Tato, PhD
University of Alabama at Birmingham
Unexpected Role(s) for IRF5 Risk Variants in SLE Pathogenesis
Betsy Jo Barnes, PhD
The Feinstein Institute for Medical Research
Neutrophil Elastase as a Therapeutic Target in Lupus
Jason S. Knight, MD, PhD
University of Michigan Medical School
Characterization of Chemokine Producing Effector B Cells in SLE
Frances E. Lund, PhD
University of Alabama at Birmingham
Targeting Nicotinic Receptors to Reduce Inflammation Associated With SLE
Keisa Williams Mathis, PhD
University of Texas Health Science Center at Fort Worth
Targeting Immunometabolism and Co-stimulation in Combination Therapies in Lupus
Laurence Morel, PhD
University of Florida College of Medicine
Regulation of CD11c+Tbet+ B Cells in Lupus
Alessandra B. Pernis, MD
The Hospital for Special Surgery
Mechanisms of the Autoimmune Germinal Center Response in SLE
Ziaur Rahman, MD, PhD
Pennsylvania State University College of Medicine
Targeting EZH2 in Lupus
Amr Sawalha, MD
University of Michigan Medical School
2016 Funded Grants
Autophagy components and B cell activation During SLE
Mridu Acharya, PhD
Benaroya Research Institute at Virginia Mason
Anti-BDCA 2-Targeted Therapy for SLE
Natalia Giltiay, PhD
University of Washington
B cell-Intrinsic Cytokine Reg of Spontaneous Germinal CTR Formation in SLE
Shaun Jackson MD, PhD
Seattle Children’s Hospital
Multi-level Biomarkers for Psychiatric Disorders in Pediatric Lupus
Andrea Knight, MD
The Children’s Hospital of Philadelphia
Targeting type II NKT Cells for a Novel Therapeutic in Lupus
Vipin Kumar, PhD
University of California, San Diego
Impaired Mitochondrial Clearance in Systemic Lupus Erythematosus
Christian Lood, PhD
University of Washington
Mitochondria, Caspases and Type I interferons in Autoimmunity
Anthony Rongvaux, PhD
Fred Hutchinson Cancer Research Center
Cathepsin S Inhibitor-Modified Treg Cells Mitigate Murine SLE
Guo-Ping Shi, DSc
Brigham and Women’s Hospital
A Novel Approach for Treating Lupus by Inhibiting Fli1 Transcription Factor
John Zhang, DVM, PhD
Medical University of South Carolina
Oxidized Mitochondrial DNA Employs APEX1 in Neutrophils to Control Lupus
Zhiqiang Zhang, PhD
The Methodist Hospital Research Institute
2015 Funded Grants
Role of Infection in Obstetric Antiphospholipid Syndrome
Vikki M. Abrahams, PhD
Yale University
Therapeutic Selective Targeting of BAFF Receptors
Julio A. Camarero, PhD
USC/University of Southern California
Pesticides and Chemical Exposures, DNA Methylation, and SLE Phenotypes
Lindsey Ann Criswell, MD, MPH
University of California, San Francisco
Bacterial Amyloids from Biofilms Break Tolerance in Lupus
Stefania Gallucci, MD
Temple University
Understanding the Pathway Regulated by the Lupus Susceptibility Gene Ets1
Lee Ann Garrett-Sinha, PhD
The Research Foundation for The SUNY University at Buffalo
Repopulation of Tolerogenic B Cells Post B Cell Depletion Therapy in Lupus
Hui-Chen Hsu, PhD
The University of Alabama at Birmingham
IDO2, A Novel Therapeutic Target for the Treatment of Lupus
Laura Mandik-Nayak, PhD
Lankenau Institute for Medical Research
Tolerogenic Dendritic Cells in Human Lupus
Timothy B. Niewold, MD
New York University School of Medicine
Sex disparity in Lupus is Driven by Putative X-Linked Genes
Robert Hal Scofield, MD
The University of Oklahoma Health Sciences Center
Cross Sectional and Longitudinal Studies of Immune Complexes in SLE
Barbara J. Vilen, PhD
The University of North Carolina at Chapel Hill
A Free Website for Discovering Non-Coding Lupus- Associated Variant Function
Matthew T. Weirauch, PhD
Cincinnati Children’s Hospital Medical Center, Research Foundation
PLK1, a Potential Novel Therapeutic Target for Lupus
Tianfu Wu, PhD
University of Houston
because the Lupus Research Alliance board of directors funds all administrative and fundraising costs