Targeting Endogenous Glomerular Repair in Lupus Nephritis

Dr. Janos Peti-Peterdi studies what goes wrong with the kidneys in people with lupus and how kidneys damaged by lupus can be repaired. He has developed a pioneering research technique, known as “intravital imaging,” to use a highly sensitive microscope to directly examine in fine detail the kidneys in an animal model of lupus. He will also test two potential treatments for lupus nephritis and observe whether they are effective at repairing the kidneys by regenerating damaged cells. Using the insights and data gained as a springboard, Dr. Peti-Peterdi will then focus his research on patients with lupus nephritis to find ways to help their kidneys heal. x

What this study means to people with lupus

This research project promises to improve treatment of lupus nephritis for the benefit of all patients with this serious complication.