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Category: Research and Discovery

Better Survival Rates from Severe Lupus Nephritis

September 20, 2018 Significantly more people are surviving end-stage renal (kidney) disease caused by lupus nephritis according to a long-term analysis published in Arthritis & Rheumatology. The analysis of the national registry of 20,974 patients with end-stage renal disease (ESRD) during the years 1995 through  2014 found that mortality rates significantly declined.  In addition, among […] Read More

Our Grantees Lead Investigation of Microbiome in Lupus

Sept. 5, 2018 Our microbiome includes all of the trillions of microorganisms that live in and on us. A recent review article about key discoveries on the role of the microbiome in lupus includes two researchers funded by the Lupus Research Alliance who may have discovered how some of these microbial passengers promote lupus by […] Read More

Hearst Foundations Awards Grant to Lupus Research Alliance

August 22, 2018 The Lupus Research Alliance is proud to once again be awarded the Health Grant from the Hearst Foundations. In the amount of $150,000, the highly sought Health Grant will help support two promising investigators relatively new to lupus who were recently awarded our Novel Research Grants, Drs. Andrea Knight and Vipin Kumar. […] Read More

Inflammation Trigger Discovery May Lead to New Treatment

August 2, 2018 Inflammation helps us repair injuries and defeat infections. It’s supposed to shut down once a crisis is over. In people with lupus, however, inflammation persists and can damage the joints, skin, and organs. Researchers have discovered a molecular sensor in cells known as the NLRP3 inflammasome that triggers inflammation. When the inflammasome […] Read More

Neovacs Announces the Results of its Phase IIb Study for Ifnalpha Kinoid in the Treatment of Lupus Which Allows to Proceed With the Clinical Development into Phase III

July 3, 2018 Neovacs announced the results of its Phase IIb clinical trial of the investigational agent IFNalpha Kinoid in patients with moderate to severe lupus (SLE). The results show that IFNalpha Kinoid very significantly reduced the levels of type I interferon genes in the blood and tissue cells of people with lupus. High levels […] Read More

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