Epigenetic Regulation of Il2 by ATF7ip – Implications for SLE
Michael Waterfield, MD, PhDUniversity of California, San Francisco (Contracts & Grants)
Examining the Role of T cell Exhaustion in Lupus Pathogenesis
Novel Research Grants (Novel)
Novel Research Grants offer up to $100,000/year total costs for up to 3 years. They provide early stage support for highly innovative approaches to major challenges in lupus research. Special emphasis is placed on lupus studies exploring fundamental mechanisms, novel targets and pathways, novel technologies, and interdisciplinary approaches.
2018 Funded Grants
University of California, San Francisco (Contracts & Grants)
Examining the Role of T cell Exhaustion in Lupus Pathogenesis
Jeremy Tilstra, MD, PhDUniversity of Pittsburgh
Genetically Engineering Regulatory T Cells to Treat SLE
Joshua Ooi, PhDMonash University
Age-Associated B cells in Autoimmune Lupus
Kevin Nickerson, PhDUniversity of Pittsburgh
Ferroptosis as a novel driver of inflammation in lupus nephritis
Erika Boesen, PhDUniversity of Nebraska Medical Center
Lymphatic Regulation and Photosensitivity
Theresa Lu, MD, PhDThe Hospital for Special Surgery
2017 Funded Grants
Targeting EZH2 in Lupus
Amr Sawalha, MDUniversity of Michigan Medical School
Unexpected Role(s) for IRF5 Risk Variants in SLE Pathogenesis
Betsy Jo Barnes, PhDThe Feinstein Institute for Medical Research
Neutrophil Elastase as a Therapeutic Target in Lupus
Jason S. Knight, MD, PhDUniversity of Michigan Medical School
Immunotargeting of T Follicular Helper (Tfh) Cells for SLE Treatment
Andre Ballesteros-Tato, PhDUniversity of Alabama at Birmingham
Mechanisms of the Autoimmune Germinal Center Response in SLE
Ziaur Rahman, MD, PhDPennsylvania State University College of Medicine
Regulation of CD11c+Tbet+ B Cells in Lupus
Alessandra B. Pernis, MDThe Hospital for Special Surgery
Targeting Immunometabolism and Co-stimulation in Combination Therapies in Lupus
Laurence Morel, PhDUniversity of Florida College of Medicine
Targeting Nicotinic Receptors to Reduce Inflammation Associated With SLE
Keisa Williams Mathis, PhDUniversity of Texas Health Science Center at Fort Worth
Characterization of Chemokine Producing Effector B Cells in SLE
Frances E. Lund, PhDUniversity of Alabama at Birmingham
2016 Funded Grants
Oxidized Mitochondrial DNA Employs APEX1 in Neutrophils to Control Lupus
Zhiqiang Zhang, PhDThe Methodist Hospital Research Institute
Autophagy components and B cell activation During SLE
Mridu Acharya, PhDBenaroya Research Institute at Virginia Mason
B cell-Intrinsic Cytokine Reg of Spontaneous Germinal CTR Formation in SLE
Shaun Jackson MD, PhDSeattle Children’s Hospital
A Novel Approach for Treating Lupus by Inhibiting Fli1 Transcription Factor
John Zhang, DVM, PhDMedical University of South Carolina
Cathepsin S Inhibitor-Modified Treg Cells Mitigate Murine SLE
Guo-Ping Shi, DScBrigham and Women’s Hospital
Mitochondria, Caspases and Type I interferons in Autoimmunity
Anthony Rongvaux, PhDFred Hutchinson Cancer Research Center
Impaired Mitochondrial Clearance in Systemic Lupus Erythematosus
Christian Lood, PhDUniversity of Washington
Targeting type II NKT Cells for a Novel Therapeutic in Lupus
Vipin Kumar, PhDUniversity of California, San Diego
Multi-level Biomarkers for Psychiatric Disorders in Pediatric Lupus
Andrea Knight, MDThe Children’s Hospital of Philadelphia
Anti-BDCA 2-Targeted Therapy for SLE
Natalia Giltiay, PhDUniversity of Washington
because the Lupus Research Alliance board of directors funds all administrative and fundraising costs